In an analysis of data from the first two school years of the Shape Up Somerville: Eat Smart Play Hard™ intervention, Tufts University researchers showed that schoolchildren in Somerville, Massachusetts gained less weight and were less likely to be obese or overweight than schoolchildren in two similar control communities.
For the first time, researchers have restored significant bladder function through nerve regeneration in rats with the most severe spinal cord injuries (SCI). The breakthrough paired a traditional nerve bridge graft with a novel combination of scar degrading and growth factor treatments to grow new nerve cells from the thoracic level to the lower spinal cord region.
The media often portray computer scientists as nerdy males with poor social skills. But a UW psychologist found women will want to study computer science if they don't buy into the stereotypes.
UCLA researchers have found that older adults who regularly used a brain-fitness program on a computer demonstrated significantly improved memory and language skills.
A team of scientists with the Wildlife Conservation Society, BirdLife International, and other groups have discovered a new species of bird with distinct plumage and a loud call living not in some remote jungle, but in a capital city of 1.5 million people.
A new approach to teaching pre-kindergarten could take a bite out of the achievement gap and level the playing field for America’s growing population of English language learners, according to a recently published study by researchers at Vanderbilt’s Peabody College of education and human development.
Nearly 30 female materials scientists and engineers tell their stories in "United in Our Differences: Changing the Face of MSE," an extensive feature package in the July 2013 issue of JOM.
Gabriela Ilie, Ph.D., of St. Michael's Hospital, Toronto, Canada, and colleagues, examined the prevalence of TBI, mechanisms of injury, and adverse correlates in a large representative sample of adolescents living in Ontario, Canada.
In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.
Use of advanced treatment technologies for prostate cancer, such as intensity-modulated radiotherapy and robotic prostatectomy, has increased among men with low-risk disease, high risk of noncancer mortality, or both, a population of patients who are unlikely to benefit from these treatments, according to a study in the June 26 issue of JAMA.
Researchers at Boston University College of Health & Rehabilitation Sciences: Sargent College have identified a combinatorial therapeutic approach that has proven effective in treating muscular dystrophy in a mouse model.
According to a study of physicians’ attitudes about pain drugs published in The Journal of Pain, negative physician attitudes about opioid medications are closely associated with lower rates of prescribing and more favorable attitudes are linked with higher prescribing levels.
For treating the estimated 100 million Americans with chronic pain -- a population larger than those with heart disease, cancer and diabetes combined -- researched reported in The Journal of Pain shows that primary care physicians overwhelmingly prefer to prescribe non-steroidal anti-inflammatory medications (NSAIDS), in accordance with published clinical practice guidelines.
A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches. Although prior studies have found it safe to delay treatment and monitor some presumably slow-growing or low-risk prostate cancers, such “active surveillance” (AS) does not appear to be a good idea for black men, the study concludes.
Nursing homes with higher proportions of Black residents do worse financially and deliver lower-quality care than nursing homes with few or no Black residents, finds a new study in Health Services Research.
A study found that people who are blindfolded employ the same strategy to intercept a running ball carrier as people who can see, which suggests that multiple areas of the brain cooperate to accomplish the task.
Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it’s the most common lymphoma subtype while in dogs, it’s one of the most common cancers in veterinary oncology.
An international team of astronomers has found that a nearby star previously thought to host two or three planets is in fact orbited by six or seven worlds, including an unprecedented three to five "super-Earths" in its habitable zone.
Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells. These fragments can be used as targets for tumor-infiltrating lymphocytes that have been shown to reduce cancerous lesions.
Leading experts on water issues in the Western U.S. have come together to establish what is known about the future of Colorado River water, and to understand the wide range of estimates for future flows.
Researchers have demonstrated that a protein called caspase-2 is a key regulator of a signaling pathway that leads to cognitive decline in Alzheimer's disease. The findings, made in a mouse model of Alzheimer's, suggest that inhibiting this protein could prevent the neuronal damage and subsequent cognitive decline associated with the disease. The study was published this month in the online journal Nature Communications.
How much is too much? It depends on how you say it – especially on a restaurant menu. Cornell University research reveals that descriptions of portion size impacts how much we eat and how much we’re willing to pay for our food.
Researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute have uncovered for the first time the vital role a popular protein plays in the stroma, the cell-lined area outside of a prostate tumor.
Resurrecting ancient proteins in the lab, researchers discover just two mutations set the stage for the evolution of modern hormone signaling.
In the June 25 issue of the Annals of Internal Medicine, Scott Halpern, MD, PhD, MBE, medical ethicist and assistant professor of ≈, Division of Pulmonary, Allergy and Critical Care, at the Perelman School of Medicine at the University of Pennsylvania, discusses the implications of judicial activism in organ donation and suggests several ways to improve the availability and allocation of transplantable organs.
Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism, and bipolar disorder, according to new research by UC San Francisco scientists.
A new nanoscale transistor made by Michigan Technological University scientists could represent the next frontier in electronics.
Overweight or obese adolescents who were spoken to about their weight by their mothers and fathers were more likely to engage in binge eating and use unhealthy weight-control behaviors than teens whose parents spoke with them in terms of eating healthier, according to a study published in JAMA Pediatrics. “I often do not even have my pediatric patients weigh themselves facing the scale; the number is not the goal,” says Ashley Barrient, MEd, LPC, RD, LDN, dietician and bariatric counselor at Loyola Center for Metabolic Surgery & Bariatric Care. “Kids are overwhelmed by talk of weight and dieting and feel they cannot change the numbers. But if you talk with them about the whole family making healthy eating changes as a team, they feel supported and positive change happens more frequently.”
The excess risk of death from ischemic (due to reduced blood flow), but not hemorrhagic (due to bleeding), stroke in US black children has decreased over the past decade, according to a study by Laura L. Lehman, M.D., of Boston Children’s Hospital, and colleagues.
Conversations between parents and adolescents that focus on weight and size are associated with an increased risk for unhealthy adolescent weight-control behaviors, according to a study published Online First by JAMA Pediatrics, a JAMA Network publication.
Hospital performance on publicly reported conditions (acute myocardial infarction [heart attack], congestive heart failure, and pneumonia), may potentially be used as a signal of overall hospital mortality rates, according to a study by Marta L. McCrum, M.D., of Harvard School of Public Health, Boston, and colleagues.
Postmenopausal hormone therapy with conjugated equine estrogens (CEEs) was not associated with overall sustained benefit or risk to cognitive function when given to women ages 50 to 55 years, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.
Dana-Farber Cancer Institute scientists provide the first statistically-based guidelines for determining whether stem cell transplant is appropriate for patients older than 60 with myelodysplastic syndromes (MDS).
Some open-minded people can be swayed to support government intervention on climate change – but only if they are presented with both the benefits and the costs, a new study suggests.
The clues that parents give toddlers about words can make a big difference in how deep their vocabularies are when they enter school, new research at the University of Chicago shows. By using words to reference objects in the visual environment, parents can help young children learn new words, according to the research.
Researchers led by M. Mahmood Hussain, PhD, found that a regulatory RNA molecule interferes with the production of lipoproteins and, in a mouse model, reduces hyperlipidemia and atherosclerosis.
In an analysis that included a sample of patients in the top portion of Medicare spending, only a small percentage of their costs appeared to be related to preventable emergency department visits and hospitalizations, limiting the ability to lower costs for these patients through better outpatient care, according to a study in the June 26 issue of JAMA.
Sophisticated new optical quality metrics can identify older adults likely to have more rapid age-related declines in vision, suggests a study, “Factors Accounting for the 4-Year Change in Acuity in Patients Between 50 and 80 Years”, in the July issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Teens and young adults are making use of social networking sites and mobile technology to express suicidal thoughts and intentions as well as to reach out for help, two studies suggest.
The goal of restoring or creating wetlands on agricultural lands is almost always to remove nutrients and improve water quality. But new research shows that constructed marshes also excel at pulling carbon dioxide from the air and holding it long-term in soil, suggesting that farmers and landowners may also want to build wetlands to "farm" carbon.
Scientists led by a UCSF neurology researcher are reporting that they have identified the likely genetic mechanism that causes some patients with multiple sclerosis (MS) to quickly progress to a debilitating stage of the disease while other patients progress much more slowly.
Two new Baylor University studies show that Israeli Jewish adults who attend synagogue regularly, pray often, and consider themselves religious are significantly healthier and happier than their non-religious counterparts. They also report greater satisfaction with life.
The findings of the published study suggest that the intramuscular treatment with placenta-based cell therapies may serve as a highly effective “off the shelf” therapy to mitigate Acute Radiation Syndrome (ARS).
Compared with adults already enrolled in Medicaid, low-income uninsured adults who may be eligible for Medicaid under the Affordable Care Act were less likely to have chronic conditions such as hypertension, diabetes, and hypercholesterolemia, although those with 1 of these conditions were less likely to be aware they had it or to have the disease controlled, according to a study in the June 26 issue of JAMA.
Development of skin cancer may require changes in the genes that control cell shape, report a team of scientists from three institutions in an upcoming issue of Nature Cell Biology. The work could lead to a better understanding of how the cells become metastatic.
Therapeutic hypothermia is rarely being used in patients who suffer cardiac arrest while in the hospital, despite its proven potential to improve survival and neurological function, researchers from Penn Medicine report in the June issue of Critical Care Medicine. The findings have implications for the lives of 210,000 patients in U.S. who arrest during hospitalizations each year.
Scientists from the Florida campus of The Scripps Research Institute have shown in animal models that brain damage caused by the loss of a single copy of a gene during very early childhood development can cause a lifetime of behavioral and intellectual problems.
Seeds gobbled by birds and dispersed across the landscape tend to fare better than those that fall near parent plants. Now it turns out it might not just be the trip through the air that's important, but also the inches-long trip through the bird.
University of Delaware chemist Joel Rosenthal and doctoral student John DiMeglio have developed an inexpensive catalyst that uses the electricity generated from solar energy to convert carbon dioxide into synthetic fuels.
A new review by researchers at the University of Maryland School of Medicine highlights a large body of published research demonstrating how modified citrus pectin (MCP), works against cancer. The study, which was published on April 18 in the American Journal of Pharmacology and Toxicology, also examines MCP’s synergistic relationship with chemotherapy, as well as its ability to modulate immunity, safely remove heavy metals and block the pro-inflammatory protein galectin-3.
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