Four Penn Medicine postdoctoral trainees have been awarded three-year fellowships through a newly established program, the Michael Brown Penn-GSK Postdoctoral Fellowship Award Program from the Perelman School of Medicine at the University of Pennsylvania, in partnership with GlaxoSmithKline.
New research provides details of how the structure of the HIV-1 virus is assembled, findings that offer potential new targets for treatment.
Children and adolescents living in households without access to nutritious foods benefit greatly by participating in federally funded nutrition programs, according to an updated position paper by the Academy of Nutrition and Dietetics.
Inducing labor in healthy first-time mothers in the 39th week of pregnancy results in lower rates of cesarean sections compared with waiting for labor to begin naturally at full term, according to a multicenter study funded by the National Institutes of Health (NIH). Additionally, infants born to women induced at 39 weeks did not experience more stillbirths, newborn deaths or other major health complications.
Inducing labor in healthy women at 39 weeks into their pregnancy reduces the need for cesarean section and is at least as safe for mother and baby as waiting for spontaneous labor. Choosing to induce could also reduce the risk that mothers will develop preeclampsia and that newborns will need respiratory support after delivery, according to a study publishing in the New England Journal of Medicine on August 8.
Before Medicaid work requirements get into full gear, a team of Medicaid researchers is offering specific recommendations to help states ensure that they don’t harm the health of people enrolled in Medicaid. They recommend focusing on adults under 50 in expansion plans, clearly guiding physicians on certifications, offering services to support working and job-seeking enrollees, and spacing out reporting periods to fit modern work patterns.
To understand why some patients with appendix cancer respond to standard treatment while others do not, University of California San Diego School of Medicine and Moores Cancer Center researchers, in collaboration with Foundation Medicine, performed genetic profiling on 703 appendiceal tumors — the largest such study of this disease to date — to compare mutations present in both cancer types.
“Safe consumption sites,” where people can use pre-obtained drugs with medically trained personnel on hand to treat overdoses, garner higher public support when they are called “overdose prevention sites,” according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.
A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.
Accurate Diagnosis and Proper Management Could Improve Outcomes
Researchers found that babies exposed to Suboxone in utero fared as well as, or better than babies exposed to more conventional addiction treatments, such as treatment with methadone or Subutex.
Exercise can help prevent relapses into cocaine addiction, according to new research led by the University at Buffalo’s Panayotis (Peter) Thanos, PhD.
Northern Arizona University ecologist Andrew Richardson used PhenoCam, a network of automated digital cameras, to track this unusual effect of climate change.
A study in Nature revealed that turning up the heat accelerates spring greening in vegetation and delays fall color change. The research team measured plant greenness over three years at the SPRUCE study, a unique ecosystem-scale experiment operated by DOE’s Oak Ridge National Laboratory.
Checkpoint inhibitor therapies have made metastatic melanoma and other cancers a survivable condition for 20 to 30 percent of treated patients, but clinicians have had very limited ways of knowing which patients will respond. Researchers have uncovered a novel mechanism by which tumors suppress the immune system. Their findings also usher in the possibility that a straightforward blood test could predict and monitor cancer patients’ response to immunotherapy.
Scientists have designed a way to monitor cellular decision making by measuring the rate of RNA change over time. RNA is the “interpreter” or “decoder” of genetic instructions that tell cells how much of which protein to make. The new method is an algorithm that quantifies changes in various RNA markers—the molecular footprints of a cell’s past and present and an indicator of its future, providing clues about what the cell is trying to become. The approach sets the stage for understanding cellular behavior during human development and may offer a way to rapidly monitor how cells respond to medications and other treatments.
In a new study, Johns Hopkins researchers found that fewer than half of interviewed caregivers for Baltimore preschool children with asthma were prepared to administer medication for routine management or emergency response to a child's chronic condition.
University of Colorado Cancer Center study shows that common laboratory tests used to determine ROS1 status may return false-negative results, meaning that some patients who could benefit from ROS1-directed therapy may be slipping through the cracks.
Mice deficient in innate lymphoid cells are vulnerable to lethal infection by the bacterial pathogen Yersinia enterocolitica (YE), which causes some forms of food poisoning. Moreover, activation by a cytokine called LIGHT, which is a member of the tumor necrosis factor (TNF) superfamily, is necessary for ILCs to mount an anti-bacterial response.
The batteries of the future may be made out of paper. Researchers at Binghamton University, State University at New York have created a biodegradable, paper-based battery that is more efficient than previously possible
Scientists identify a safe drug that for the first time could treat – and possibly reverse – the thickening of lung artery walls in pulmonary arterial hypertension; clinical trial is expected in 2019
A new study at Texas Biomedical Research Institute is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to establish replication.
Field history matters when trying to apply the optimal amount of nitrogen for sweet potato crops. Cover crops grown in the same plots prior to sweet potato crops affected how much nitrogen was needed.
In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.
Inspired by elements found in nature, researchers at the University of New Hampshire say the puzzle-like wavy structure of the delicate seed coat, found in plants like succulents and some grasses, could hold the secret to creating new smart materials strong enough to be used in items like body armor, screens, and airplane panels.
A team led by scientists at Berkeley Lab found a way to make a liquid-like state behave more like a solid, and then to reverse the process.
Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications.
The second annual edition of “Forces On and Within Cells, a special issue of Molecular Biology of the Cell, the peer-reviewed journal of the American Society for Cell Biology (ASCB), launched August 8, online.
Sleep-related infant deaths are associated with bed-sharing, sleeping position, poverty and other factors
Jorge Henao-Mejia will work to uncover how minute organisms in the gut contribute to obesity and type 2 diabetes, findings which could pave the way from new treatments to reduce the ever-growing number of people diagnosed with these serious medical conditions.
Young children and their families in poor communities were able to make some achievable and sustainable behavioral changes during the longest and largest obesity prevention intervention, but, in the end, the results were insufficient to prevent early childhood obesity.
The first-ever computation of an atomic nucleus, the deuteron, on a quantum chip demonstrates that even today’s rudimentary quantum computers can solve nuclear physics questions.
Virtually all functions in our bodies require precise interactions between radically different types of molecules. Researchers at The University of Texas at Dallas are pursuing what differentiates a fruitful encounter from a dud.
Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills called statins can effectively treat the disease.
Not only can your smartphone serve as your wallet, watch and map, it can also be your digital security blanket. In a new study led by the University of California, Irvine, researchers found that when people are in awkward social situations, having their phones with them offers comfort and helps relieve feelings of isolation.
Proton-irradiated thorium targets are successfully mined for therapeutic radium isotopes.
A study led by researchers at Indiana University has found that human changes to rivers and streams in the United States and Canada do not isolate these natural resources from the effects of climate change.
"In humans, being able to tweak levels of TTR degradation could act as a means of stopping TTR toxicity."
روتشستر، مينيسوتا. – حدد فريق البحث الذي تتولى قيادته Mayo Clinic جينات معينة ترتبط بزيادة خطر الإصابة بسرطان الثدي الثلاثي السلبي. وقد تم نشر أبحاث الفريق اليوم في مجلة المعهد الوطني للسرطان.
由Mayo Clinic领导的一个研究小组已经确认了与三阴性乳腺癌（triple-negative breast cancer）风险增加相关的特定基因。 他们的研究成果于今天发表在《国家癌症研究所杂志》（Journal of the National Cancer Institute）上。
- Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Salk Institute for Biological Studies, have generated the first single cell resolution atlas of genes that control the formation of breast tissue. The atlas provides a comprehensive molecular map that will be used to help researchers understand how breast cancers form and to pinpoint new ways to prevent, diagnose, and treat the disease.
Getting wisdom teeth removed may be a rite of passage for many teens and young adults, but the opioid painkiller prescriptions that many receive could set them on a path to long-term opioid use, a new study finds. Young people who filled an opioid prescription were nearly 2.7 times as likely as peers to still be filling opioid prescriptions months later.
An intervention designed to promote healthy growth that taught first-time moms how to respond with age-appropriate responses to their babies’ needs resulted in children having lower body mass indexes (BMIs) when they were three years old.
400 kilometers above Earth, researchers examined waves in complex plasma under microgravity conditions and found that the microparticles behaved in nonuniform ways in the presence of varying electrical fields. They report some of the first findings from the Plasma-Kristall 4 experiment, a collaboration between the European Space Agency and the Russian State Space Corporation Roscosmos, in Physics of Plasmas.
In nature, the nuclear reactions that form stars are often accompanied by astronomically high amounts of energy, a challenge for nuclear astrophysicists trying to study these reactions; the chances of re-creating such a spark are unfathomably low. However, after recent renovations to its accelerator, one laboratory reported record-breaking performance. Following six years of upgrades to the Electron Cyclotron Resonance Ion Source at the Laboratory for Experimental Nuclear Astrophysics, researchers report improved results, discussed in Review of Scientific Instruments.
Metastasis is a leading contributor to many deaths related to cancer, but the exact mechanisms for how broken cellular function appears in cells far removed from a cancer’s primary tumor remain an area of ongoing research. Scientists at the University of Minnesota Twin Cities confirmed a link between healthy-tumor hybrid cells and metastatic tumors for the first time in live animals. In APL Bioengineering, they discuss how they studied the distinct, heterogenous gene expression profiles found in human hybrid cells and how hybrid cells spontaneously occur in mouse models.
An in-depth study of retired football and hockey players—including cognitive, psychological, and brain imaging techniques—finds no increase in the rate of early-onset dementia, reports the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of America, JHTR is published by Wolters Kluwer.
Uma equipe de pesquisa liderada pela Mayo Clinic identificou genes específicos associados a um maior risco de desenvolver câncer de mama triplo-negativo. A pesquisa foi publicada hoje no Journal of the National Cancer Institute.
روتشستر، مينيسوتا. – أشارت دراسة أولية نُشرت في عدد أغسطس الصادر من Mayo Clinic Proceedings أن بكتيريا الأمعاء قد تكون مسؤولة لدى بعض الأشخاص عن عدم قدرتهم على إنقاص الوزن، على الرغم من التزامهم باتباع نظام غذائي صارم وتمارين رياضية منتظمة Mayo Clinic Proceedings.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right