The University of Delaware will lead an interdisciplinary team that has received a $6 million grant to probe how viruses impact microbes critical to our lives, from producing oxygen to growing food.
One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA. A team of Vanderbilt University researchers have worked out the molecular details that explain how this bacterial toxin—yatakemycin (YTM)—kills cells by preventing DNA replication.
Bio-Rad Laboratories, Inc., a global provider of life science research and clinical diagnostic products, announces the launch of recombinant Luteinizing Hormone (LH), which expands the company’s Critical Raw Material offerings.
As neuroscientists examine challenging questions about the complexities of the central nervous system, new tools to be developed at Cornell University will provide them with an unprecedented glimpse into the inner workings of the brain thanks to a five-year, $9 million grant from the National Science Foundation.
Scientists have used the “mirror box” illusion – an old magic trick – in a number of neuroscience studies. Researchers at the University of Delaware are using a new version of the illusion to study how the brain processes multiple sensory inputs to perceive our bodies and the world around us.
Each cell in the body is made up of a number of tiny sealed membranous subunits called organelles, and they send things like lipids back and forth to allow the cell to function. A process called membrane tethering is responsible for bridging the gap between organelles, and now, Texas A&M researchers have discovered a way to manipulate this tethering. The study was the cover story in the journal Chemical Science.
Diener Precision Pumps, the leading manufacturer of precision piston pumps and gear pumps announces the introduction of a new enhanced Precision Series piston pump at the AACC this year in San Diego.
Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT. The winner of the Qualcomm Tricorder XPRIZE competition will present DxtER—a real-life tricorder—at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego. This special session will be the first time that the device is presented to researchers at a U.S. scientific conference.
A team of researchers at the University of California San Diego School of Medicine and the Salk Institute for Biological Studies describe development and application of new electron microscopic imaging tools and a selective stain for DNA to visualize the three-dimensional structure of chromatin — a complex of molecules that helps pack six feet of DNA into each cell nucleus, construct chromosomes and control gene expression and DNA replication.
Hexokinase (HK, EC 2.7.1.1) is an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate is the most important product. Hexokinase can transfer an inorganic phosphate group from ATP to a substrate.
The findings, published today in Cell, reveal for the first time components of a G protein–coupled receptor (GPCR) named rhodopsin bound to a signaling molecule called arrestin, both crucial pieces of the body’s intricate cellular communication network. The new discovery further refines a landmark 2015 Nature article that first described the structure of the two molecules in complex together.
Through the “Facilities Integrating Collaborations for User Science” (FICUS) initiative, 6 proposals have been selected to participate in a new partnership between the DOE Joint Genome Institute and the National Energy Research Scientific Computing Center, both U.S. Department of Energy user facilities at Lawrence Berkeley National Laboratory.
An international team of scientists has developed a method to rapidly produce specific human antibodies in the laboratory. The technique, which will be described in a paper to be published July 24 in The Journal of Experimental Medicine, could speed the production of antibodies to treat a wide range of diseases and facilitate the development of new vaccines.
In saliva, scientists have found hints that a “ghost” species of archaic humans may have contributed genetic material to ancestors of people living in Sub-Saharan Africa today.
The research adds to a growing body of evidence suggesting that sexual rendezvous between different archaic human species may not have been unusual.
It lives in boiling acid that dissolves flesh and bone. Now scientists have unlocked the secrets of the indestructible virus, potentially allowing them to harness its remarkable properties to create super-durable materials and better treat disease.
Researchers have developed a technique that uses the vibration of chemical bonds to produce specific colors that allow them to simultaneously observe, in cells and tissues, as many as 24 interacting molecules--each with a distinct color.
Northwestern University neuroscientists now can visualize how fruit flies sense and process humidity. The findings could one day help researchers better understand how the human brain simultaneously processes humidity and temperature and might influence how humans control for mosquitoes in cities and prevent mosquito-borne disease
Harvard Medical School researchers have discovered a new regulatory mechanism for genomic imprinting, the process that silences one parent’s gene so that only the other parent’s gene is expressed in offspring.
For some developmental genes one allele must stay silent, otherwise debilitating syndromes and cancers can arise. HHMI Investigator Yi Zhang and his colleagues have uncovered a new imprinting mechanism cells use to keep these genes quiet in mice.
XimedicaDx, formerly known as Accel Biotech, is proud to unveil their comprehensive rebranding, which is officially being revealed at the 69th AACC Clinical Lab Expo in San Diego. The change comes in alignment with their acquisition by Ximedica, a leading full service medical technologies development firm, in July of 2016. XimedicaDx maintains Accel Biotech’s comprehensive experience and expertise in in-vitro diagnostics and life science product development as Ximedica’s Diagnostics Center of Excellence.
Sébastien Praud, Biogemma Genetics and Genomics in Cereals team leader, has been appointed to the Board of the International Wheat Genome Sequencing Consortium.
JADAK, a business unit of Novanta Corporation, is exhibiting at the 69th annual AACC Clinical Lab Expo from August 1st – 3rd, 2017 in San Diego, CA, Booth #2818. JADAK’s exhibit will feature its new Clarity™ 2.0 Machine Vision & Image Analysis Software, demonstrated within a desktop analyzer, as well as its expanded line of Ultra High Frequency (UHF) RAIN RFID products and Near Field Communications (NFC) High Frequency (HF) RFID product line
Scientists at the University of Washington have discovered a simple way to raise the accuracy of diagnostic tests for medicine and common assays for laboratory research. By adding polydopamine — a material that was first isolated from shellfish — to these tests at a key step, the team could increase the sensitivity of these common bioassays by as many as 100 to 1,000 times.
The DOE has announced funding for new research centers to accelerate the development of specialty plants and processes for a new generation of biofuels and bioproducts.
Abraxis, Inc., announces expansion of its AbraMag magnetic beads line for molecular biology, biochemistry and sample prep applications, with the addition of mRNA purification beads and kit.
Research from the University of Notre Dame have improved their method of tracking species by using the biological material those organisms leave behind known as environmental DNA (eDNA).
Ludwig researchers show how a method that physically expands tissues can improve early breast cancer diagnostics and extend the capabilities of ordinary pathology labs
Scientists may be able to use self-assembly to design new materials with custom characteristics. Understanding self-assembly is particularly important for working with nanoparticles. Scientists supported by the Department of Energy are investigating two major methods of self-assembly. They are looking into both particles that assemble on their own as well as “nano-Velcro” that can pull together particles that wouldn’t otherwise connect on their own.
A feature article published this afternoon in the new, online nonprofit journalism news outlet Bioengineering Today explores the global, billion-dollar industry of wearable fitness and medical technologies, which stands at the crossroads of computing, consumer electronics, exercise culture and human health.
Spark Therapeutics announces publication in The Lancet of pivotal Phase 3 data at year one for investigational voretigene neparvovec an investigational, potential one-time gene therapy candidate for the treatment of patients with vision loss due to confirmed biallelic RPE65-mediated inherited retinal disease (IRD).
Scientists at HHMI’s Janelia Research Campus created comprehensive brain maps linking different groups of neurons to specific behaviors, using a machine-learning program that annotated more than 225 days of videos of flies – a feat that would have taken humans some 3,800 years.
In collaboration with staff from the Argonne Leadership Computing Facility, researchers at the National Cancer Institute have perfected a technique that accurately computes the 3-D structure of RNA sequences. This method, which relies on a computer program known as RS3D and supercomputer Mira gives researchers studying cancer and other diseases structural insights about associated RNAs that can be used to advance computer-assisted drug design and development.
Today, the U.S. Department of Energy (DOE) announced the selection of three projects to receive up to $8 million, aimed at reducing the costs of producing algal biofuels and bioproducts.
While the Zika virus is primarily transmitted by mosquitoes, research has shown that the disease can affect semen and sperm and can therefore be spread through sexual intercourse.
Researchers are reporting progress in developing a method to accurately determine the functional age of cells, a step that could eventually help clinicians recommend ways to delay some health effects of aging and potentially improve treatments.
Sysmex America, Inc., a leading provider of automated hematology and urinalysis diagnostic testing equipment as well as middleware information systems technology, today announced that it has launched its XN-L™ automated hematology analyzers in the United States. The new, smaller XN-L line delivers the same globally-proven, clinical and operational value known in its XN-Series™ to lower volume hematology laboratories. The XN-L analyzers will also be the first to feature BeyondCareSM Quality Monitor, a revolutionary approach to quality assurance.
In the same year the University of Florida’s Citrus Research and Education Center celebrates its 100th anniversary, Nian Wang believes he may be close to finding the “off switch” for greening, the disease devastating Florida’s multi-billion-dollar-a-year citrus industry.
By taking a series of near-atomic resolution snapshots, Cornell University and Harvard Medical School scientists have observed step-by-step how bacteria defend against foreign invaders such as bacteriophage, a virus that infects bacteria.
Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations. UT Southwestern researchers have hit upon a novel way to do that.