A five-year, $3.2 million grant from the National Institutes of Health will help a research team including faculty at Binghamton University, State University of New York explore serotonin's role in Parkinson's disease.
مدينة روتشستر، ولاية مينيسوتا- يشكل السرطان والعَدوى وأمراض القلب الخطر الأكبر على متلقي زراعة الكلى- وليس رفض الأعضاء - وفقًا لدراسة مايو كلينك المنشورة مؤخرًا، حيث اكتشف الباحثون أن وفاة المتلقي إثر عوامل أخرى غير رفض العضو هي السبب الرئيسي لفقدان الكلى المزروعة. فواحدة فقط من كل 4 حالات لفقدان الكلى المزروعة تكون بسبب رفض العضو.
根据最近发表的一项妙佑医疗国际(Mayo Clinic)研究，对肾移植受者危害最大的是癌症、感染和心脏病，而不是器官排斥。研究人员发现，由于器官排斥以外的因素导致的受者死亡是移植肾丢失的主要原因。只有1/4的移植肾丢失是由器官排斥造成的。
While COVID-19 disease significantly impacts many pregnant women, the rates of transmission from mother to baby in pregnancy are very low.
Our sensory systems provide us with immediate information about the world around us. Researchers have created the first sensory map for smell. The map details how the fruit fly’s olfactory receptor neurons, the components that sense smell, are organized within the insect’s sensory hairs.
Prisons and jails have been fertile ground for COVID-19 outbreaks, leading to millions of cases in the United States. Individuals released from these facilities often transition to other congregate settings, such as homeless shelters and group homes, where COVID-19 infections can continue to spread. Now, Albert Einstein College of Medicine and Montefiore Health System have been awarded a five-year, $3.4 million grant from the National Institutes of Health (NIH) to test a program aimed at reducing SARS- CoV-2 transmission among people recently released from incarceration.
A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines. The research is a collaboration between Trudeau Institute, Texas Biomedical Research Institute’s Southwest National Primate Research Center (SNPRC), and Walter Reed Army Institute of Research (WRAIR), where the vaccine was developed.
_RGB Blue20230706101098.jpg&width=400&height=400)
A Case Western Reserve dental school researcher was awarded $3.7M in NIH grants to study the link between people living with HIV and higher rates of cancer and other diseases.
Researchers have developed a new method of measuring motor imitation, adding to a growing set of computational behavior analysis tools that can detect and characterize motor differences in children with autism.
A team of experts at Children’s Hospital Los Angeles has received $8.3 million from the National Institutes of Health (NIH) to study long-term effects of COVID-19 in children and young adults in order to determine the most effective ways to treat the serious consequences of this condition.
National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss. The method quantifies disease-related loss of light-sensing retina cells, yielding information for monitoring patients, understanding genetic causes of the disease, and developing therapies to treat it.
National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss. The method quantifies disease-related loss of light-sensing retina cells, yielding information for monitoring patients, understanding genetic causes of the disease, and developing therapies to treat it.
Researchers at the Icahn School of Medicine at Mount Sinai discovered that the chance a pathogenic genetic variant may actually cause a disease is relatively low - about 7 percent. They also found that some variants, such as those associated with breast cancer, are linked to a wide range of risks for disease. The results could alter the way the risks associated with these variants are reported, and one day, help guide the way physicians interpret genetic testing results.
Researchers have developed a comprehensive sequencing test specifically for mitochondrial DNA (mtDNA). This new clinical diagnostic test provides important information as to whether and to what level variations in the mtDNA are present in different tissues from a patient with suspected mitochondrial disease, leading to more precise diagnosis and more personalized treatment options.
Researchers are studying whether a drug already approved to treat neurodegenerative diseases can be repurposed to help trauma surgeons determine whether nerves are severed or non-severed in peripheral nerve injuries.
Scientists find metabolites that were consistently linked with coronary heart disease among Black individuals.
A five-year, $23 million award from the National Institutes of Health will put Cornell at the center of a significant federal investment in research aimed at customizing nutrition guidance.
An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, leading to improved weight control, according to a new study in mice from researchers at Washington University School of Medicine in St. Louis.
Tufts' HNRCA will lead a new study to develop algorithms to predict how individuals respond to different food and dietary patterns. Funded by the National Institutes of Health, researchers are hopeful the initiative will lead to more personalized nutrition guidance.
National Institutes of Health establishes Microbiome and Metagenomics Center at UC San Diego, part of new effort to predict individual responses to food and inform personalized nutrition recommendations.
A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease. The study suggests that the drug has the potential to treat COVID-19 patients, including those who are infected with aggressive SARS-CoV-2 variants.
Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body. Moreover, fat processing hormones may play a central role in coordinating this activity. That is the primary result of a study that began nearly 20 years ago on a hunch and involved hundreds of coronary artery disease patients from Northern Europe. The study was led by researchers at the Icahn School of Medicine at Mount Sinai.
Some prostate cancers might also include a small number of aggressive cells hiding among the indolent ones like wolves in a herd of sheep. Researchers at Duke Health have identified a molecular signature that can spot these lurking threats.
A new study by Wistar researchers has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).
Cancer, infections and heart disease pose the greatest risk to kidney transplant recipients ― not organ rejection ― according to a recently published Mayo Clinic study. Researchers discovered that recipient death due to factors other than organ rejection is the leading cause for transplanted kidney loss. Only 1 in 4 transplanted kidney losses were caused by organ rejection.
• Researchers have identified a set of receptors shared across human, mosquito, and other animal cells for the eastern equine encephalitis virus (EEEV) and two related viruses, a crucial first step for developing preventive and curative treatments. • In experiments with cells and mouse models with a related virus, the scientists were able to prevent infection and disease progression using decoy molecules to hamper viral entry into cells. • In a 2019 outbreak of eastern equine encephalitis (EEE, or triple E) in New England, 30 percent of infected people died and half of those who survived had long-term neurologic damage. • Done between major outbreaks, this type of research into highly pathogenic viruses with pandemic potential can help improve preparedness for future outbreaks.
UC San Diego researchers report successfully removing the nucleus from a type of ubiquitous cell, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.
Physician researchers from UT Southwestern Medical Center have developed an innovative nanotherapeutic drug that prevents cancer from spreading to the liver in mice.
Researchers studying how small worms defend themselves against pathogens have discovered a gene that acts as a first-line response against infection. They identified “ZIP-1” as a centralized hub for immune response, a finding could have implications for understanding human immunity against viruses.
Sanford Burnham Prebys professor Andrei Osterman, Ph.D., has been awarded a $3.6 million grant from the National Institutes of Health (NIH) to expand current knowledge of antibiotic resistance, which will inform more precise antibiotic prescribing practices and help researchers develop drugs that are harder for bacteria to resist.
A new study published Jan. 13 in Science reports that Epstein-Barr virus infection – known for causing mononucleosis or “mono,” could be a primary cause for multiple sclerosis.
An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.
With this NIH grant, FAU researchers are developing an affordable, disposable self-testing HIV-1 chip that can selectively detect HIV from whole blood samples, be highly sensitive to detect HIV during the acute infection, treatment and viral rebound; be rapid within 40 minutes; highly stable without requiring refrigeration; and fully automated providing true sample-in-answer-out ability.
Two recent studies by Dana-Farber Cancer Institute scientists correct a longstanding misconception about the origins of Barrett’s esophagus, and in doing so may point to new avenues of treatment or prevention to lower the risk of esophageal cancer.
A Wayne State University School of Medicine researcher has secured a $2.5 million grant to develop an effective mobile management intervention program to improve asthma control in young Black American adults.
A study in mice led by UCLA researchers shows that removing chemical messengers in the brain that are involved in both wakefulness and addiction may make withdrawal from opioids easier and help prevent relapse.
Florida State University researchers have identified a link between two key parts of the brain that play significant roles in conditions such as Alzheimer’s disease, post-traumatic stress disorder, schizophrenia and depression.Associate Professor of Psychology and Neuroscience Wen Li and psychology doctoral candidate Kevin Clancy found that stimulating the system in the brain that deals with attention and imagery also enhances the efficiency of what’s called the default mode network, a key part of the brain’s functional organization.
Understanding how cells die is key to developing new treatments for many diseases, whether the goal is to make cancer cells die or keep healthy cells alive in the face of other illnesses, such as massive infections or strokes. Two new studies from Washington University School of Medicine in St. Louis have identified a previously unrecognized pathway of cell death — named lysoptosis — and demonstrate how it could lead to new therapies for cervical cancer.
The discovery raises the possibility that some of the roughly two million new cases of colorectal cancer every year around the world originate from brief and seemingly mild food-poisoning events.
In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells. The advance could move scientists a step closer to being able to reduce the amount of virus, or even eliminate it, from infected people.
Researchers at Penn Medicine have discovered a new, more effective method of preventing the body’s own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy’s effectiveness.
Higher levels of antioxidants – particularly manganese antioxidants – could potentially extend one’s lifespan and radiation resistance, according to a new study published on Jan. 11 in mBio by researchers at the Uniformed Services University of the Health Sciences (USU).
Irvine, Calif., Jan. 10, 2022 – A team led by University of California, Irvine researchers has developed a new biopsy technology that can profile multiple tumor microenvironment biomarkers simultaneously, revealing cellular spatial organization and interactions that will help advance personalized disease diagnosis and treatment.
the NIH Collaboratory is donning a new name—NIH Pragmatic Trials Collaboratory—that will carry the highly successful program into the future with a continued commitment to transforming clinical research. The program was formerly known as the NIH Health Care Systems Research Collaboratory. Its new moniker reflects the program’s core mission of strengthening the national capacity to implement cost-effective, large-scale research studies conducted within healthcare delivery systems, also known as pragmatic trials.
A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain’s hippocampal formation. The team identified novel functional roles of new circuit connections between the venal CA1 region and dorsal CA3 regions of the hippocampus and demonstrated that genetic inactivation of this projection impairs object-related spatial learning and memory, but does not modulate anxiety-related behaviors.
An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.
Researchers have discovered that bacterial communities are far more advanced than previously believed. Scientists found that biofilm cells are organized in elaborate patterns, a feature previously only associated with higher-level organisms such as plants and animals.
First-responder cells launching the repair after a heart attack are so frantic about fixing the damage that they promote more inflammation than necessary, new research in mice suggests. Scientists are pursuing interventions that would bring more balance to the healing process after a heart attack.
A $2.1 million NIH grant will enable Northern Arizona University mechanical engineer Zach Lerner to launch a major clinical trial to test a treatment strategy for children with cerebral palsy using a lightweight, wearable robotic device.
For the first time, University of California, Irvine researchers in collaboration with the Max-Planck Institute of Biochemistry, have revealed, at a molecular level, key structural determinants of the highly specialized rod outer segment (ROS) membrane architecture of the eye, which is instrumental to vision.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
