SYnAbs and Univercells, two neighboring companies based in Gosselies, Belgium, today announce strategic deal signature. Under the terms of the agreement, SYnAbs will develop an immuno-assay in order to measure a confidential biosimilar monoclonal antibody developed by Univercells.
A new research report shows an increase in patients being prescribed opioids after experiencing an ankle sprain. The Michigan Medicine authors urge fellow physicians to be aware of the current treatment guidelines.
A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it’s disabled or depleted in mouse models, tumors shrank significantly.
César de la Fuente, PhD, has joined the Perelman School of Medicine at the University of Pennsylvania as a Presidential Assistant Professor in the departments of Psychiatry and Microbiology, in addition to the department of Bioengineering at Penn.
Despite the shortage of EpiPens over the last year, other autoinjectors are available in pharmacies and should be considered by anyone who has a severe allergy that might result in anaphylaxis.
Research indicates that virtually every day, millions of children and adolescents are being bombarded by sexually explicit direct-to-consumer advertising, despite pharmaceutical CEOs’ claims to the contrary.
This research is a fundamental discovery of how to engineer proteins onto non-biological surfaces. Artificial proteins engineered from scratch have been assembled into nanorod arrays, designer filaments and honeycomb lattices on the surface of mica, demonstrating control over the way proteins interact with surfaces to form complex structures previously seen only in natural protein systems. The study provides a foundation for understanding how protein-crystal interactions can be systematically programmed and sets the stage for designing novel protein-inorganic hybrid materials.
NJIT Mechanical and Industrial Engineering Professor Dibakar Datta and his team used the Comet supercomputer at the San Diego Supercomputer Center (SDSC), located at the University of California San Diego, to create detailed simulations of graphene-water interactions to determine if graphene is a good candidate for delivering medicine to a specific part of the body.
The herb kratom is increasingly being used to manage pain and treat opioid addiction, but it’s not safe to use as an herbal supplement, according to new research led by faculty at Binghamton University, State University of New York.
A million times a year, pneumonia sends American adults to the hospital. And while antibiotics help save lives, a new study shows two-thirds receive more antibiotics than they probably need.
The males of one species of butterfly are more attracted to females that are active, not necessarily what they look like, according to a recent research conducted at Augustana University.The paper, “Behaviour before beauty: Signal weighting during mate selection in the butterfly Papilio polytes,” found that males of the species noticed the activity levels of potential female mates, not their markings.
Irvine, Calif., July 8, 2019 — The University of California, Irvine Institute for Interdisciplinary Salivary Bioscience Research has received a five-year, $1 million gift from the Elisabeth Severance Prentiss Foundation for expansion of a study using saliva rather than blood to monitor lithium levels in patients with bipolar and major depressive disorders.
Irvine, Calif., July 8, 2019 — University of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells to target and kill cancer bone metastases while preserving the bone. This new approach, reported in the journal EBioMedicine, equips engineered mesenchymal stem cells with targeting agents that drive them to bone metastatic sites, where they offload therapeutics.
A new Cornell University-led study describes the first successful rearing of engineered tobacco plants in order to produce medical and industrial proteins outdoors in the field, a necessity for economic viability, so they can be grown at large scales.
An interdisciplinary team of UCLA scientists has found that small cell neuroendocrine cancers from a range of tissues have a common molecular signature and share drug sensitivities with blood cancers.
By dispensing a year's worth of birth control pills up front, the VA could prevent 583 unintended pregnancies and save $2M per year on health care costs each year.
In a recent Journal of Infectious Diseases study, investigators showed using two antibiotic drugs to fight P. aeruginosa in mouse models was significantly more effective than either antibiotic alone. The antibiotics were ceftazidime-avibactam
John Bing, BSN, CRNA, a Certified Registered Nurse Anesthetist from Clarksville, MD., has been elected as a Fellow in the American Academy of Nursing (AAN).
Nobel Prize-winning Directed evolution is an artificial, sped up process to make a protein perform a specified task. UNC School of Medicine scientists created a powerful new directed evolution technique for the rapid development of scientific tools and new treatments for many diseases.
Mayo Clinic研究人员开展的一项新研究可能对治疗主要良性甲状腺疾病和首次接受甲状腺功能减退治疗的患者具有深远的意义。
Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Medicare Part D enrollees may pay more out of pocket for high-priced specialty generic drugs than their brand-name counterparts, according to new research by health policy experts at Vanderbilt University Medical Center and the University of North Carolina at Chapel Hill.
ASA today announced Heron Therapeutics, Inc., a developer of novel, pharmaceutical treatments to reduce postsurgical pain and for patients with cancer, has joined ASA’s Industry Supporter Program to support the Society’s more than 53,000 physician anesthesiologists members and improve patient care.
UC San Diego School of Medicine researchers identified chemical compounds that prevent stress-induced clumping of TDP-43 protein in ALS motor neurons grown in the lab — a starting point for new ALS therapeutics.
A team of researchers found that DNA damaged by the widely used chemotherapy drug cisplatin is almost fully repaired in noncancerous tissue within two days. These results could inform the timing of chemotherapy strategies and improve their efficacy.
Whether it’s a rare treat or a weekly routine, many older adults enjoy spending time with grandchildren. But a new poll suggests many could do more to reduce the risk of their medications harming their grandchild. More than 80% keep their medication in its usual place when grandchildren visit them – and 72% keep medicines in their purse or bag when visiting grandchildren.
Chemists at UC San Diego present a promising method for easing the synthesis and evaluation of the algorithms, chemistry and technology needed to predict the bound poses of ligands within a targeted protein—a necessity for the design of new drug therapies.
In a new study published in JAMA Network Open, University of Kentucky researchers, in collaboration with researchers from Ferris State University, examined whether legal mandates on naloxone coprescription in certain states increased naloxone dispensing.
Every year, millions of Americans misuse or abuse prescription medications, sometimes leading to emergency room visits, addiction or even death. The problem has worsened amid the ongoing opioid crisis. To prevent drugs from falling into the wrong hands, it's more important than ever to dispose of unused pills in a safe and smart way -- and simply throwing them away or even flushing them down the toilet are actually very dangerous options.
After a personal experience with a patient inspired him to make some changes, Dr. Phillip Chang worked with pharmacist Doug Oyler to initiate a small pilot study in UK HealthCare's trauma service with the goal of reducing opioid prescriptions. That small study has grown and created a "culture change" at UK HealthCare, drastically reducing the number of opioid prescriptions written and reducing high-risk opioid use by 57 percent.
Um novo estudo feito por pesquisadores da Mayo Clinic pode ter grandes implicações para o tratamento de pacientes com doença benigna da tireoide e hipotiroidismo recém-tratado.
The American Society of Anesthesiologists (ASA) and Society for Education in Anesthesia (SEA) today announced a call for nominations for the new ASA-SEA Distinguished Educator in Anesthesiology award. The award recognizes mid-career physicians who have demonstrated a substantial commitment and achievement as educators in the field of anesthesiology.
Scientists at UAB have identified an enzyme in the brain, LIMK1, that may be an intriguing target for interventions against Alzheimer’s disease and other dementia due to its interactions with dendritic spines.
In a new study, aimed at using stem cells for hair growth, Columbia researchers have created a way to grow human hair in a dish, which could open up hair restoration surgery to more people, including women, and improve the way pharmaceutical companies search for new hair growth drugs.
A new mathematical model of the structure of networks could help find new cancer drugs, speed up traffic flow and combat sexually transmitted disease. Although the three challenges seem diverse, they all could benefit from a theory that helps uncover information about a network by analyzing its structure. The study was published in the journal Chaos. Successful link prediction algorithms already exist for certain types of networks, but the researchers analyzed differently structured networks to come up with their alternative algorithm.
People with chronic diseases like arthritis, diabetes and heart disease may one day forego the daily regimen of pills and, instead, receive a scheduled dosage of medication through a grape-sized implant that is remotely controlled.
Women exposed to triclosan are more likely to develop osteoporosis, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Two-year program is the first of its kind in the United States to provide students with the knowledge needed to support patients and the medical cannabis industry, add to existing research, and develop well-informed medical cannabis policy.
In July’s SLAS Discovery feature article, “3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis,” Tijmen H. Booij, Ph.D., Screening Specialist for NEXUS Personalized Health Technologies (Switzerland), discusses the switch from using 2D to 3D cell cultures in drug discovery to more accurately mimic human physiological conditions and improve the success rates of drugs in the early stages of preclinical drug discovery.
The University of Illinois at Chicago will work with TB Alliance to help find new drug treatments for tuberculosis, a bacterial infection considered to be one of the leading causes of death worldwide. The goal is to produce two new clinical-stage drug candidates for treating tuberculosis, which is becoming increasingly resistant to available antibiotics.
Intrexon Corporation (Intrexon) (NASDAQ: XON), a leader in the engineering and industrialization of biology to improve quality of life and health of the planet
Pregnant women are often advised to avoid certain drugs because of potential risks to their unborn infant's growing brain cells.
Virginia Tech, with the Fralin Biomedical Research Institute and its clinical partner Carilion Clinic, will serve as one of the national anchor research and clinical sites to validate a test for mild Traumatic Brain Injury. The test combines injury-related blood-protein biomarkers with computerized neurological assessments at the point of care.
The extract successfully restored the blood glucose levels, body weight, and normalized oxidative stress on renal function in a test group of Zucker diabetic fatty rats.
Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.
Researchers have made a hydrogel that, when injected near tumors in mice, recruits drugs to shrink the tumor with fewer side effects. They report their results in ACS Central Science.
Nurses play a critical role in promoting compassionate care for patients and families affected by alcohol use disorder (AUD), including evidence-based medication-assisted treatment (MAT) approaches, according to a paper in the July/September Journal of Christian Nursing, official journal of the Nurses Christian Fellowship. The journal is published in the Lippincott portfolio by Wolters Kluwer.
L’Institut et hôpital neurologiques de Montréal (le Neuro) dirigera un partenariat en science ouverte en vue de la mise au point de médicaments de précision indiqués dans la sclérose latérale amyotrophique (SLA) et la maladie de Parkinson (MP).
Cost of current method limits availability and generates harmful waste products.
The Neuro (Montreal Neurological Institute and Hospital) will lead an open science partnership to develop precision drugs for amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD).
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