Curated News: PNAS

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29-Jan-2021 9:45 AM EST
CHOP Researchers Demonstrate How Defects in Mitochondria May Lead to Autism Spectrum Disorder
Children's Hospital of Philadelphia

Researchers have demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells.

28-Jan-2021 8:20 AM EST
Mysterious Magnetic Fossils Offer Past Climate Clues
University of Utah

There are fossils, found in ancient marine sediments and made up of no more than a few magnetic nanoparticles, that can tell us a whole lot about the climate of the past, especially episodes of abrupt global warming. Now, researchers have found a way to glean the valuable information in those fossils without having to crush the scarce samples into a fine powder.

27-Jan-2021 3:05 PM EST
New clues emerge in how early tetrapods learned to live — and eat — on land
University of Chicago Medical Center

New research out of the University of Chicago has found evidence that the lobe-finned fish species Tiktaalik roseae was capable of both biting and suction during feeding, similar to modern-day gars. These results provide evidence that bite-based feeding originally evolved in aquatic species and was later adapted for use on land.

Released: 1-Feb-2021 12:30 PM EST
Latch, load and release: Advanced Photon Source helps reveal elastic motion that makes click beetles click
Argonne National Laboratory

A new study examines the forces behind the quick energy release beetles use for propulsion and provides guidelines for studying extreme motion and energy storage and release in animals.

Released: 25-Jan-2021 5:20 PM EST
Finding a way to stop chemotherapy from damaging the heart
Ohio State University

There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.

Released: 20-Jan-2021 10:50 AM EST
Where do our minds wander? Brain waves can point the way
University of California, Berkeley

Anyone who has tried and failed to meditate knows that our minds are rarely still. But where do they roam? New research led by UC Berkeley has come up with a way to track the flow of our internal thought processes and signal whether our minds are focused, fixated or wandering.

   
Released: 19-Jan-2021 2:30 PM EST
Land deals meant to improve food security may have hurt
University of Notre Dame

Large-scale land acquisitions by foreign investors, intended to improve global food security, had little to no benefit, increasing crop production in some areas while simultaneously threatening local food security in others, according to Notre Dame researchers who studied their effects.

Released: 19-Jan-2021 9:20 AM EST
Story tips: Volcanic microbes, unbreakable bonds and flood mapping
Oak Ridge National Laboratory

ORNL story tips: Volcanic microbes, unbreakable bonds and flood mapping

Released: 18-Jan-2021 12:05 PM EST
UCLA Fielding School of Public Health Researchers Say Mask Mandates Could add $1 Trillion to the U.S. GDP
UCLA Fielding School of Public Health

The team, including UCLA Fielding School of Public Health professors Anne Rimoin and Christina Ramirez, found that near-universal adoption of nonmedical masks in public, combined with complementary public health measures, could successfully eliminate spread of the infection. and add $1 Trillion to the U.S. GDP.

Released: 14-Jan-2021 4:45 PM EST
Toadlet Peptide Transforms Into a Deadly Weapon Against Bacteria
American Technion Society

An international team of researchers has discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.

Released: 14-Jan-2021 11:35 AM EST
Discrimination may increase risk of anxiety disorders regardless of genetics, study finds
Tufts University

Exposure to discrimination plays a significant role in the risk of developing anxiety and related disorders, even – in a first – after accounting for potential genetic risks, according to a multidisciplinary team of health researchers led by Tufts University and the Harvard T.H. Chan School of Public Health.

   
Released: 12-Jan-2021 10:00 AM EST
The Odd Structure of ORF8: Scientists Map the Coronavirus Protein Linked to Disease Severity
Lawrence Berkeley National Laboratory

A team of biologists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells. The structural map has laid the groundwork for new antiviral treatments and enabled further investigations into how the newly emerged virus ravages the human body.

   
8-Jan-2021 8:10 AM EST
Ocean Acidification is Transforming California Mussel Shells
University of California San Diego

As the waters off our coasts change due to human influences, scientists have found that the composition of shells of California mussels, a critical species found along the Pacific Coast, are weakening as a result of ocean acidification.

Released: 5-Jan-2021 11:00 AM EST
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Released: 23-Dec-2020 4:20 PM EST
New Wireless Wearable Sensors Monitor Brain Blood Flow and Oxygenation in Vulnerable Pediatric Patients
Ann and Robert H. Lurie Children's Hospital of Chicago

An interdisciplinary team from Northwestern University and Ann & Robert H. Lurie Children’s Hospital of Chicago developed and clinically tested soft, flexible, miniaturized sensors that gently adhere to the child’s forehead to wirelessly monitor changes in cerebral blood flow and oxygenation, to alert clinicians of potential need to intervene and restore equilibrium. Findings were published in the Proceedings of the National Academy of Sciences (PNAS).

Released: 22-Dec-2020 1:15 PM EST
Slow start of plate tectonics despite a hot early Earth
University of Cologne

Writing in PNAS, scientists from Cologne university present important new constraints showing that plate tectonics started relatively slow, although the early Earth's interior was much hotter than today.

Released: 21-Dec-2020 5:40 PM EST
New engine capability accelerates advanced vehicle research
Oak Ridge National Laboratory

In the quest for advanced vehicles with higher energy efficiency and ultra-low emissions, Oak Ridge National Laboratory researchers are accelerating a research engine that gives scientists and engineers an unprecedented view inside the atomic-level workings of combustion engines in real time.

Released: 21-Dec-2020 12:15 PM EST
Digging Deep For Differences In Duchenne Muscular Dystrophy
UT Southwestern Medical Center

DALLAS – Dec. 21, 2020 – A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans. The findings, published online recently in PNAS, could lead to new treatments for this devastating degenerative disease and insights into factors that affect muscle development.

Released: 21-Dec-2020 10:30 AM EST
Prostate cancer regulator plays role in COVID-19, providing a promising treatment lead
Michigan Medicine - University of Michigan

By taking a lesson from prostate cancer, researchers now have a promising lead on a treatment for COVID-19. They found that, just like in prostate cancer, TMPRSS2 is regulated by the androgen receptor in the lungs. And notably, blocking the androgen receptor led to lower expression of TMPRSS2, which led to decreased coronavirus infection in mice and cellular models.

Released: 21-Dec-2020 8:10 AM EST
Speeding Toward Improved Hydrogen Fuel Production
Lawrence Berkeley National Laboratory

A new material developed by a team led by Berkeley Lab's Molecular Foundry will help to make hydrogen a viable energy source for a wide range of applications, including stationary power and portable power applications.

Released: 18-Dec-2020 12:30 PM EST
Researchers discover new way to deliver DNA-based therapies for diseases
University of Minnesota College of Science and Engineering

University of Minnesota Twin Cities researchers have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the researchers were able to see exactly how polymers interact with human cells when delivering medicines into the body. This discovery opens the door for more widespread use of polymers in applications like gene therapy and vaccine development.

   
Released: 17-Dec-2020 2:45 PM EST
UCI engineers reveal molecular secrets of cephalopod powers
University of California, Irvine

Irvine, Calif., Dec. 17, 2020 — Reflectins, the unique structural proteins that give squids and octopuses the ability to change colors and blend in with their surroundings, are thought to have great potential for innovations in areas as diverse as electronics, optics and medicine. Scientists and inventors have been stymied in their attempts to fully utilize the powers of these biomolecules due to their atypical chemical composition and high sensitivity to subtle environmental changes.

17-Dec-2020 8:05 AM EST
Scientists Set a Path for Field Trials of Gene Drive Organisms
University of California San Diego

A broad coalition that includes UC San Diego scientists sets commitments for field trials of powerful gene drive technology. The multidisciplinary group encourages trials that are safe, transparent and ethical.

Released: 14-Dec-2020 11:35 AM EST
Researchers Discover Clue to How to Protect Neurons and Encourage Their Growth
UC San Diego Health

Researchers have identified a family of enzymes whose inhibition both protects neurons and encourages their growth, a pathway to potential new treatments for neurodegenerative diseases from Alzheimer’s to glaucoma.

Released: 10-Dec-2020 5:15 PM EST
Restorative justice preferred among the Enga in Papua New Guinea
University of Utah

A study analyzing 10 years of court cases of the Enga of Papua New Guinea show that they overwhelmingly emphasize restorative justice, allowing all sides to share their side of the story, the community assists paying compensation to the victim, and supports reintegrating the offender back into society.

Released: 8-Dec-2020 8:00 AM EST
How The Brain Remembers Right Place, Right Time
UT Southwestern Medical Center

DALLAS – Dec. 8, 2020 – Two studies led by UT Southwestern researchers shed new light on how the brain encodes time and place into memories. The findings, published recently in PNAS and Science, not only add to the body of fundamental research on memory, but could eventually provide the basis for new treatments to combat memory loss from conditions such as traumatic brain injury or Alzheimer’s disease.

4-Dec-2020 4:40 PM EST
Undocumented immigrants far less likely to commit crimes in U.S. than citizens
University of Wisconsin–Madison

Crime rates among undocumented immigrants are just a fraction of those of their U.S.-born neighbors, according to a first-of-its-kind analysis of Texas arrest and conviction records.

Released: 2-Dec-2020 4:10 PM EST
New activity found for CHD7, a protein factor vital in embryonic development
University of Alabama at Birmingham

Researchers inactivated the gene for CHD7 — whose mutation causes congenital birth defects — in mouse embryos, and then rigorously probed how this change in developing cardiac neural crest cells caused severe defects in the outflow tract and great arteries, leading to perinatal lethality.

Released: 1-Dec-2020 12:10 PM EST
An escape route for seafloor methane
Massachusetts Institute of Technology (MIT)

Methane, the main component of natural gas, is the cleanest-burning of all the fossil fuels, but when emitted into the atmosphere it is a much more potent greenhouse gas than carbon dioxide.

Released: 30-Nov-2020 3:30 PM EST
New Tech Can Get Oxygen, Fuel From Mars’ Salty Water
Washington University in St. Louis

A new electrolysis system that makes use of briny water could provide astronauts on Mars with life-supporting oxygen and fuel for the ride home, according to engineers at the McKelvey School of Engineering at Washington University in St. Louis, who developed the system.

30-Nov-2020 9:15 AM EST
Virginia Tech researchers show teens with risk-averse peers make safer choices
Virginia Tech

In a new study published today in the Proceedings of the National Academy of Sciences, Virginia Tech neuroscientists at the Fralin Biomedical Research Institute at VTC show that observing peers making sound decisions may help young people play it safe. The discovery may one day inform measures to help teens make healthy decisions.

Released: 24-Nov-2020 12:15 PM EST
Stronger memories can help us make sense of future changes
Washington University in St. Louis

Research from the Department of Psychological & Brain Sciences in Arts & Sciences finds a new relationship between memory and the ability to incorporate changes into one's understanding of the world.

Released: 24-Nov-2020 8:00 AM EST
Researchers Reveal Switch Used in Plant Defense Against Animal Attack
University of California San Diego

Researchers have identified the first key biological switch that sounds an alarm in plants when plant-eating animals attack. The mechanism will help unlock a trove of new strategies for improved plant health, from countering crop pest damage to engineering more robust global food webs.

Released: 23-Nov-2020 3:45 PM EST
Researchers identify genetics behind deadly oat blight
Cornell University

A multi-institution team co-led by a Cornell University researcher has identified the genetic mechanisms that enable the production of a deadly toxin called Victorin – the causal agent for Victoria blight of oats, a disease that wiped out oat crops in the U.S. in the 1940s.

Released: 23-Nov-2020 3:30 PM EST
Antimicrobial Soap Additive Worsens Fatty Liver Disease in Mice
UC San Diego Health

Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.

23-Nov-2020 10:30 AM EST
New Clues Shed Light On Importance Of Earth’s Ice Sheets
Florida State University

Study Stems from Antarctic Expedition to Drill Through Glaciers

20-Nov-2020 8:50 AM EST
Moths strike out in evolutionary arms race with sophisticated wing design
University of Bristol

Ultra-thin, super-absorbent and extraordinarily designed to detract attention, the wings of moths could hold the key for developing technological solutions to survive in a noisy world.

Released: 23-Nov-2020 10:45 AM EST
SFU researchers examine which approaches are most effective at reducing COVID-19 spread
Simon Fraser University

Simon Fraser University professors Paul Tupper and Caroline Colijn have found that physical distancing is universally effective at reducing the spread of COVID-19, while social bubbles and masks are more situation-dependent.

   
Released: 18-Nov-2020 5:05 PM EST
Data access restrictions reduce diversity in scientific research, study finds
University of California, Berkeley Haas School of Business

New technologies have allowed governments and other organizations to collect large, high-quality datasets that can be used in a variety of scientific research, from economics to biology to astronomy. Yet high costs and restrictions can limit both the diversity of researchers who have access and the range of research undertaken with this valuable data.

   
Released: 13-Nov-2020 3:40 PM EST
Researchers Identify Promising New Compounds to Potentially Treat Novel Coronaviruses
University of Maryland Medical Center

Researchers at the University of Maryland School of Medicine (UMSOM) have discovered new drug compounds to potentially treat the novel coronavirus that causes COVID-19. This finding could lead to the development of new broad-spectrum antiviral drugs that target viruses such as influenza, Ebola and coronaviruses.

Released: 11-Nov-2020 7:05 PM EST
UCLA Fielding School of Public Health-led Research Yields Strategies to Keep Pandemic Under Control With Fewer Restrictions on the Economy
UCLA Fielding School of Public Health

An international team led by UCLA Fielding School of Public Health researchers has developed and tested two strategies for sustaining economic activity during the COVID-19 pandemic

Released: 11-Nov-2020 4:10 PM EST
Novel population of neurons identified that control binocular eye movements in 3D space
University of Alabama at Birmingham

Researchers have discovered a previously undescribed set of neurons called saccade-vergence burst neurons that help control our eyes as they view in three-dimensional space. Models had predicted the existence of such neurons, which are in the mid-brain’s central mesencephalic reticular formation.

Released: 10-Nov-2020 3:05 PM EST
Why do bats fly into walls?
American Friends of Tel Aviv University

Bats excel in acoustic perception and detect objects as tiny as mosquitoes using sound waves. Echolocation permits them to calculate the three-dimensional location of both small and large objects, perceiving their shape, size and texture.

Released: 10-Nov-2020 11:10 AM EST
Large, delayed outbreaks of endemic diseases possible following COVID-19 controls
Princeton University

Measures to reduce the spread of COVID-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic.

9-Nov-2020 1:30 PM EST
Diseases of despair diagnoses increase in Pennsylvania
Penn State Health

Medical diagnoses involving alcohol-related disorders, substance-related disorders and suicidal thoughts and behaviors – commonly referred to as diseases of despair – increased in Pennsylvania health insurance claims between the years 2007 and 2018, according to researchers.

6-Nov-2020 12:40 PM EST
A better understanding of coral skeleton growth suggests ways to restore reefs
University of Wisconsin–Madison

In a new study, University of Wisconsin–Madison physicists observed reef-forming corals at the nanoscale and identified how they create their skeletons. The results provide an explanation for how corals are resistant to acidifying oceans and suggest that controlling water temperature, not acidity, is crucial to mitigating loss and restoring reefs.

Released: 4-Nov-2020 8:05 PM EST
Dense Microgel Suspensions Reveal In-silico What Happens Under Compression
Georgia Institute of Technology

Using large-scale computer simulations, researchers have mapped out the surprising behavior and mechanics of complex particle-solvent microgel systems, learning how the “soft and squishy” particles deform, swell, de-swell, and penetrate each other as they respond to compression.

Released: 4-Nov-2020 12:10 PM EST
New multiscale view of the human brain
Universitat de Barcelona

The architecture of the brain supports cognitive and behavioural functions and it is extremely complex with connections at multiple layers that interact with each other.

   
Released: 4-Nov-2020 11:20 AM EST
Effective government saves lives in cyclones, other disasters
Cornell University

Effective national and local governments are associated with fewer deaths from tropical cyclone disasters – even in countries with similar levels of wealth and development.



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