Genetic variations, known as SNPs, in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in AACR's Cancer Discovery.
A new University of Florida study suggests a promising brain-imaging technique has the potential to improve diagnoses for the millions of people with movement disorders such as Parkinson’s disease.
U-M Health System findings identify new drug target to prevent muscle weakness and loss after common and serious knee injury among athletes.
A team of researchers led by the University of Iowa is recommending clinical guidelines that will cut the post-surgical infection rate for staph bacteria (including MRSA) by 71 percent and 59 percent for a broader class of infectious agents known as gram-positive bacteria. The recommendations come after an extensive review of hospital practices in the U.S. and are published in the British Medical Journal.
Latest research findings by scientists at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) could enable early screening of patients with hepatocellular carcinoma (HCC), a major form of liver cancer, for more aggressive treatment to improve survival rate. The researchers have also proposed a way to inactivate SALL4 - a stem cell gene - to kill HCC cells and block tumour formation.
Sleep researchers from UC Riverside and UC San Diego have identified the sleep mechanism that enables the brain to consolidate emotional memory and found that a popular prescription sleep aid heightens the recollection of and response to negative memories.
The ability to distinguish odors declines with age. A study shows that African-Americans have a greater decrease than Caucasians. This has serious consequences. Olfactory loss often leads to impaired nutrition. It can be an early warning sign of neurodegenerative diseases, and can predict death.
Nationwide school survey shows availability of sugar- and fat-laden foods and drinks.
Men who experience restless legs syndrome (RLS) may have a higher risk of dying earlier, according to research that appears in the June 12, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Young adults who deem themselves “spiritual but not religious” are more likely to commit property crimes — and to a lesser extent, violent ones — than those who identify themselves as either “religious and spiritual” or “religious but not spiritual,” according to Baylor University researchers.
Scientists have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer’s disease and healthy family members who do not carry a mutation for the disease.
Scientists at The Scripps Research Institute have found evidence that an emotion-related brain region called the central amygdala—whose activity promotes feelings of malaise and unhappiness—plays a major role in sustaining cocaine addiction.
Many plants are self-fertilizing, meaning they act as both mother and father to their own seeds. This strategy – known as selfing – guarantees reproduction but, over time, leads to reduced diversity and the accumulation of harmful mutations. A new study published in the scientific journal Nature Genetics shows that these negative consequences are apparent across a selfing plant’s genome, and can arise more rapidly than previously thought.
Genetic research published June 12 in Nature by scientists from the University of Delaware and Woods Hole Oceanographic Institution reveals active bacteria, fungi and other microbes living in 5 million-year-old ocean sediment.
Two Indiana U. studies highlight the impact work and financial stress can have on health behaviors. The lead author urges workplace wellness programs to consider such impacts as the economy sputters along.
Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer’s disease.
Mammals possess the remarkable ability to regenerate a lost fingertip, including the nail, nerves and even bone. In humans, an amputated fingertip can sprout back in as little as two months, a phenomenon that has remained poorly understood until now. In a paper published today in the journal Nature, researchers at NYU Langone Medical Center shed light on this rare regenerative power in mammals, using genetically engineered mice to document for the first time the biochemical chain of events that unfolds in the wake of a fingertip amputation. The findings hold promise for amputees who may one day be able to benefit from therapies that help the body regenerate lost limbs.
A recent study, led by researchers at the Johns Hopkins Bloomberg School of Public Health and Huashan Hospital, Fudan University, has identified a new mechanism for PZA-resistance, which provides new insight into the how this mysterious drug works. The study is available online June 12 in the journal Emerging Microbes and Infections.
Despite a critical shortage of primary care in the United States less than 25 percent of newly minted doctors go into this field and only a tiny fraction, 4.8 percent, set up shop in rural areas, according to a study just released in the “Published Ahead-of-Print” section in Academic Medicine by researchers at the George Washington University School of Public Health and Health Services (SPHHS).
How will full implementation of the Affordable Care Act (ACA) affect the work and goals of state and local public health departments—and how can public health personnel contribute to the success of health care reform? The experience in Massachusetts has some important lessons, according to an article published online by the Journal of Public Health Management and Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
People who have obstructive sleep apnea -- when a person stops breathing for periods during sleep -- have a greater risk of sudden cardiac death, according to a study published online today in the Journal of the American College of Cardiology. An estimated 12 million American adults have obstructive sleep apnea, and many of them are undiagnosed, according to the National Heart, Lung and Blood Institute (NHLBI).
Georgia Tech research published online Monday in Nature Communications indicates that diatoms stuff more iron into their silica shells than they actually need. As a result, there’s not enough iron to go around, and the added iron during fertilization experiments may stimulate less productivity than expected. The study also says that the removal of iron through incorporation into diatom silica may be a profound factor controlling the Southern Ocean’s bioavailable pool of iron, adversely affecting the ecosystem.
For patients undergoing surgery on the cervical (upper) spine, overall rates of complications and death are higher at teaching hospitals than at non-teaching hospitals, reports a study in the June 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Stress felt by dad—whether as a preadolescent or adult—leaves a lasting impression on his sperm that gives sons and daughters a blunted reaction to stress, according to a new preclinical study in the Journal of Neuroscience by researchers at the University of Pennsylvania. The findings point to a never-before-seen epigenetic link to stress-related diseases such as anxiety and depression passed from father to child.
Teenage victims of cyberbullying, defined as the use of the internet or cell phones to send hurtful and harassing messages, are more likely to develop symptoms of depression, substance abuse and internet addiction, reports a new study in the Journal of Adolescent Health.
The more an older man walks, the better his physical and mental health and his quality of life are likely to be, finds a new study in the American Journal of Health Promotion.
Teens don’t necessarily follow in their parents’ footsteps when it comes to physical activity, finds a new study in the Journal of Adolescent Health.
Most teens have unsupervised access to their prescription drugs at home, including drugs with potential for abuse, finds a new study in the Journal of Adolescent Health.
Black women with breast cancer are more likely than Hispanic or white women to experience delays in the initiation of chemotherapy or radiation after surgery, finds a new study in Health Services Research.
Victims of trauma are at higher risk of either dying or suffering a major complication if they are treated at a hospital that serves a large population of black patients, finds a new study in Health Services Research.
Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II of a clinical trial to investigate a potential new therapy for reducing the disorder’s severest symptoms. More than 100,000 Americans and several million people worldwide suffer from this genetic disorder.
Using hands-free devices to talk, text or send e-mail while driving is distracting and risky, contrary to what many people believe, says a new University of Utah study issued June 12 by the AAA Foundation for Traffic Safety.
One in six women arriving at orthopedic fracture clinics have been victims of physical, emotional, or sexual violence at the hands of an intimate partner within the past year, and one in 50 arrive as a direct result of intimate partner violence (IPV), according to the largest multinational study of its kind to date, led by McMaster University researchers. Worldwide, intimate partner violence is the leading cause of non-fatal injury to women. Musculoskeletal injuries are the second most common type of injury resulting from IPV and are often seen by orthopedic surgeons.
A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.
Researchers at the University of Michigan Comprehensive Cancer Center looked at 169 cancer clinical practice guidelines and found that none fully met standards set in 2011 by the Institute of Medicine.
St. Jude Children’s Research Hospital has found that childhood cancer survivors overwhelmingly experience a significant amount of undiagnosed, serious disease through their adult years, establishing the importance of proactive, life-long clinical health screenings for this growing high-risk population.
Educating pediatricians in their offices, and auditing their prescription patterns, encourages them to choose more appropriate antibiotics for children with common respiratory infections.
Hearing loss (HL) is a chronic condition that affects nearly 2 of every 3 adults aged 70 years or older in the United States. Hearing loss has broader implications for older adults, being independently associated with poorer cognitive and physical functioning. The association of HL with other health economic outcomes, such as health care use, is unstudied.
Simultaneously elevated levels of the biomarkers C-reactive protein, fibrinogen and leukocyte count in individuals with chronic obstructive pulmonary disease (COPD) were associated with increased risk of having exacerbations, even in those with milder COPD and in those without previous exacerbations, according to a study in the June 12 issue of JAMA.
In a study that included more than 1.5 million deliveries in Sweden, maternal overweight and obesity during pregnancy were associated with increased risk for preterm delivery, with the highest risks observed for extremely preterm deliveries, according to a study in the June 12 issue of JAMA.
In an analysis that included more than 1,700 adult survivors of childhood cancer, researchers found a very high percentage of survivors with 1 or more chronic health conditions, with an estimated cumulative prevalence of any chronic health condition of 95 percent at age 45 years, according to a study in the June 12 issue of JAMA.
An intervention consisting of clinician education coupled with personalized audit and feedback about antibiotic prescribing improved adherence to prescribing guidelines for common pediatric bacterial acute respiratory tract infections, although the intervention did not affect antibiotic prescribing for viral infections, according to a study in the June 12 issue of JAMA.
Older adults with hearing loss are more likely than peers with normal hearing to require hospitalization and suffer from periods of inactivity and depression, according to results of a new study by experts at Johns Hopkins.
Brookhaven Lab scientists create promising gold-indium oxide nanoparticles through room-temperature oxidation
It’s common wisdom that one rotten apple in a barrel spoils all the other apples, and that an apple ripens a green banana if they are put together in a paper bag. Ways to ripen, or spoil, fruit have been known for thousands of years—as the Bible can attest—but now the genes underlying these phenomena of nature have been revealed.
University of Washington researchers have demonstrated that when humans use brain-computer interfaces, the brain behaves much like it does when completing simple motor skills such as kicking a ball, typing or waving a hand. Learning to control a robotic arm or a prosthetic limb could become second nature for people who are paralyzed.
Using star-shaped block co-polymer structures as tiny reaction vessels, researchers have developed an improved technique for producing nanocrystals with consistent sizes, compositions and architectures – including metallic, ferroelectric, magnetic, semiconductor and luminescent nanocrystals.
Scientists at The Scripps Research Institute have identified key triggers of an important cancer-blocking mechanism in cells. Termed “oncogene-induced senescence,” this mechanism can block most cancer types and is commonly experienced when incipient skin cancers turn instead into slow-growing moles.
A new study from researchers at the USDA Agricultural Research Service provides information about runoff under different management practices and can help farmers choose the practice that is best for them.
A study led by researchers at the Johns Hopkins Bloomberg School of Public Health has for the first time found that a mother’s higher exposure to some common environmental contaminants was associated with more frequent and vigorous fetal motor activity. Some chemicals were also associated with fewer changes in fetal heart rate, which normally parallel fetal movements.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right