By developing brief, accessible interventions for youth psychopathology in depression, bolstered by a five-year, $2 million Early Independence Award (EIA) from the National Institutes of Health (NIH), Stony Brook University's Jessica Schleider, PhD, hopes to develop targeted treatments for teen depression.
Some of the areas of focus include cancer, addiction, environmental health, health disparities, infectious disease, translational biomedicine, and degenerative and chronic diseases. Its visionary approach addresses individual, psychosocial and institutional-level needs by synergistically enhancing institutional, faculty and student development.
Mount Sinai neuroscientist shines light on how the brain optimizes capacity to store memories across a lifetime
A new study of African Americans with poorly controlled asthma, found differences in patients’ responses to commonly used treatments. Contrary to what researchers had expected, almost half of young children in the study responded differently than older children and adults, and than white children in prior studies.
Heather Pua, MD, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a 2019 National Institutes of Health (NIH) Director’s New Innovator Award. The award, part of the High-Risk, High-Reward Research Program, is designed to support “unusually innovative research from early career investigators,” according to the NIH.
BOSTON – (October 1, 2019) – Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver’s ability to properly metabolize fat. This effect is specific to fructose. Indeed, equally high levels of glucose in the diet actually improve the fat-burning function of the liver. This explains why high dietary fructose has more negative health impacts than glucose does, even though they have the same caloric content.
Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. With the aid of a $3.4 million NIH grant, a Rutgers Cancer Institute of New Jersey investigator and others are exploring an approach that would detect these changes among children with acute lymphoblastic leukemia early during treatment. The goal is to identify a subset of patients who would benefit from a behavioral intervention or treatment clinical trial.
Researchers at Texas Biomedical Research Institute are zeroing in on a new way to target tuberculosis (TB) infection. The National Institutes of Health (NIH) has awarded a four-year, $2.8 million grant for scientists to study the role of lung macrophages (immune cells) in metabolic and inflammation responses to TB.
Carlos Carmona-Fontaine, assistant professor of biology and a member of the Center for Genomics and Systems Biology at New York University, has been selected by the National Institutes of Health (NIH) for its highly competitive New Innovator Award.
The National Institutes of Health (NIH) today announced that Zachary T. Schug, Ph.D., assistant professor in the Molecular & Cellular Oncogenesis Program at Wistar, was awarded the prestigious NIH Director’s New Innovator Award in support of his research on the link between a high sugar/fat diet, alcohol use and cancer.
A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health (NIH) to develop a novel class of peptides that are better at treating pain and don’t have the side effects of opioids. The grant is part of the NIH initiative Helping to End Addiction Long-Term (HEAL Initiative).
NIH contract award of up to $132 million will further ongoing efforts to develop a long-lasting vaccine
The University of Georgia has signed a contract with the National Institutes of Health for an initial award of $8 million to develop a new, more advanced influenza vaccine designed to protect against multiple strains of influenza virus in a single dose. The total funding could be up to $130 million over seven years if all contract options are exercised.
A small genetic study, published September 30, 2019 in Nature Genetics, identified a protein linked to many genetic variants that affect heart function. Researchers are expanding the model to other organ systems and at larger scales to create a broader understanding of genes and proteins involved.
Researchers have solved the three-dimensional structure of a protein complex involved in vertebrate vision at atomic resolution, a finding that has broad implications for our understanding of biological signaling processes and the design of over a third of the drugs on the market today.
A National Institute on Aging grant will support Penn’s Center for Neurodegenerative Disease Research to study the underlying genetic connections between Alzheimer's Disease, Parkinson's Disease, and Dementia.
University of Texas at Dallas researchers have demonstrated that imaging technology used to map the universe shows promise for more accurately and quickly identifying cancer cells in the operating room.
Millions of people with severe burns or diabetic skin ulcers could benefit from an experimental enhancement to a next-generation covering that is already healing difficult wounds.
Good bacteria that live in the guts of mammals program the metabolic rhythms that govern the body’s absorption of dietary fat.
Scientists from the UCLA Integrated Substance Abuse Programs will lead a $25 million National Institutes of Health study testing treatments, including the use of telemedicine, to help fight the opioid epidemic in rural America.
Professors Xiangmin Xu and Rozanne Sandri-Goldin, in collaboration with Professors Bert Semler and Todd Holmes at the University of California, Irvine, School of Medicine, were awarded a three-year, $4.3 million Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative grant.
A team of researchers led by Wayne State University this week received one of 375 grant awards across 41 states made by the National Institutes of Health in fiscal year 2019 to apply scientific solutions to reverse the national opioid crisis.
There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules — a signaling channel that’s found in a tiny organ on the side of your neck — effectively lowers blood pressure in obese mice, the researchers reported recently in the journal Circulation Research.
A new web-based calculator helps middle-aged women predict their risks of experiencing heart attack, stroke, hip fracture, or breast, lung or colorectal cancer within 5, 10 or 15 years.
University of California San Diego School of Medicine researchers have identified a switch controlling HIV reproduction in immune cells which can eliminate dormant HIV reservoirs.
Researchers investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients. They found the procedure to be safe and the results to be encouraging.
MD Anderson has awarded Sheryl Harris, C.N.A., the Julie and Ben Rogers Award for Excellence in Patient Care. The annual award recognizes employees who demonstrate excellence and dedication to MD Anderson’s mission to end cancer.
Rutgers School of Dental Medicine (RSDM) was awarded an $11.7 million grant from the National Institutes of Health, (NIH) for research on the combination of ibuprofen and acetaminophen as an alternative to opioids.
A new approach to producing indolent scaffolds could streamline development and production of small-molecule pharmaceuticals, which comprise the majority of medicines in use today.
UC San Diego research supplies a blueprint for a future generation of electrode sensors—notably microscopically slender diamond needles—that utilizes existing yet nontraditional materials and fabrication procedures for recording electrical signals from every neuron in the cortex at the same time.
The National Institute of Allergy and Infectious Diseases research contract is one of the largest ever awarded to UMSOM and includes an initial award of approximately $2.5 million to conduct clinical testing of influenza vaccines. Total funding over seven years could be as much as $201 million if all options are exercised in the NIAID contract.
A novel vaccine at Penn Medicine protected almost all animal subjects exposed to the herpes virus
A team of researchers, led by Philip V. Bayly in the McKelvey School of Engineering at Washington University, plans to use MRI to study the brains of healthy, uninjured individuals to create models of brain motion to enable the researchers to predict the chronic effects of repeated head impacts in both men and women.
The UM School of Medicine's Contract awarded by the National Institute of Allergy and Infectious Diseases could fund up to $201 Million in influenza research over seven years.
Studying natural defenses in maize, a staple of diets around the world, UC San Diego biologists describe how they combined an array of scientific approaches to clearly define six genes that encode enzymes responsible for the production of key maize antibiotics known to control disease resistance.
A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25% in a study published today in the New England Journal of Medicine (NEJM).
In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic behavior in pancreatic cancer cells, and that the compound 4-hydroxyacetophenone (4-HAP), known to stiffen myosin IIC-containing cells, can send it into overdrive, overwhelming the ability of cells to invade nearby tissue.
Researchers at the University of California San Diego figured out a way to combine FDA-approved ultrasound with engineered glass particles to boost the effectiveness of immunotherapy in glioblastomas.
New study suggests the gut microbiome has a role in mechanisms related to muscle strength in older adults. Researchers found differences in bacterial profiles of older adults with high and low physical function, bacterial and strength differences in mice colonized with fecal samples from the adults.
In work suggesting new therapeutic targets to fight obesity, UT Southwestern researchers have identified a novel mechanism that regulates the creation of fat in mammals.
Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to Penn State College of Medicine researchers, a computer generated-simulation allowed them to see how a toxin produced by algal blooms in saltwater might cause amyotrophic lateral sclerosis (ALS).
Exercising several times a week may delay brain deterioration in people at high risk for Alzheimer’s disease, according to a study that scientists say merits further research to establish whether fitness can affect the progression of dementia.
Two surgical procedures used to repair vaginal prolapse — hysterectomy and employing mesh support that preserves the uterus — have comparable clinical outcomes after three years, according to new data from researchers at University of California San Diego School of Medicine.
Harrington Discovery Institute at University Hospitals and Case Western Reserve University School of Medicine announce the new Harrington-Medical Scientist Training Program (Harrington-MSTP), a two-year scholarship for Case Western Reserve University MSTP students whose work has been identified as innovative, creative and having potential to progress toward clinical application.
Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3. Studying a mouse model with the same human illness — called Krabbe disease — the researchers also identified a possible therapeutic strategy.
A potential carcinogen that has been banned as a food additive is present in concerningly high levels in electronic cigarette liquids and smokeless tobacco products, according to a new study from Duke Health.
In a follow-up study conducted in South Africa, Johns Hopkins Medicine researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease. A report on the findings was published in August in EClinicalMedicine.
An international research team is perfecting a method to predict the potential clinical implications of new drugs before clinical trials even start.
Research by the Weizmann Institute of Science's Prof. Yardena Samuels shows that heterogeneity in melanoma tumors prevents effective immune responses
UPMC Children's Hospital researchers find that the presence of adult social support is linked to less violence among at-risk teen boys.
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